Ayesha Noorani

P1.038. Minimising the Systemic Effects of an Oesophageal Leak Following High Risk Myotomy Repair Using Prophylactic Endoluminal Vacuum Therapy (EVT) – Time for a Change?

Abstract Topic Benign Disease: Iatrogenic Esophageal Disease, Perforation and Postsurgical Complications Case Submission An 80 year old frail lady (ASA 2, BMI 22) was referred with progressive dysphagia, regurgitation, and unintentional weight loss. Endoscopy demonstrated a dilat...

P1.087. Advancing Immunotherapy in Oesophagogastric Cancer: A Systematic Review of CLDN18.2-Targeted CAR T-Cell and T-Cell Engager Strategies

Abstract Topic Esophageal Cancer: Adjuvant and Neo-Adjuvant Therapies Background Conventional immunotherapy strategies have shown limited efficacy in oesophagogastric adenocarcinomas compared to other solid tumours. CLDN18.2-targeted chimeric antigen receptor T cells (CAR-T) and...

P1.037. Early-Onset Oesophagogastric Adenocarcinoma: Clinicopathological Characteristics and Outcomes From a Ten-Year Tertiary Centre Experience

Abstract Topic Esophageal Cancer: Molecular Biology/Pathology Background The incidence of early-onset oesophago-gastric adenocarcinoma (EO-OGC) is rising worldwide, yet its clinicopathological characteristics and oncological outcomes remain incompletely defined. This study aimed...

P1.036. Early-Onset Gastric Cancer (EOGC): A Meta-Analysis of Risk Factors, Clinicopathological Features, and Survival Outcomes

Abstract Topic Esophageal Cancer: Other Background Early onset gastric cancer (EOGC), defined as diagnosis before 55 years, represents a growing global health challenge. Although traditionally rare, its incidence is rising and now constitutes the second most common early onset ga...