Antitumor effects of CEP32496 on urothelial carcinoma with BRAF mutation (V595E) in dogs.
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Abstract
< 0.05) in tumor growth in mice, with severe and extensive necrosis on histopathological examination. These results suggested that CEP32496 exerts antitumor effects on both cell proliferation and tumor growth in UC with V595E.
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Authors: Hirofumi Yamasaki, Hiromi Hiramatsu, Jun NAKAMICHI, Meina Tei, Yosuke Uematsu, Kazuyuki Uchida, Kenichiro Ono, Hidehiro Hirao
Institutions: The University of Tokyo