Health & Medicinearticle2026-09-10

Valproic Acid–Induced Hyperammonemic Encephalopathy: A Case Report

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Abstract

This article presents a case demonstrating that valproic acid, which is widely used in the treatment of bipolar disorder, can lead to hyperammonemic encephalopathy, a rare but potentially serious adverse effect.

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View paper (DOI)Open access versionOpenAlexDicle Medical Journal / Dicle Tip DergisiPublished 2026-09-10

Authors: Rıdvan Toprak, Rukiye Ay

Institutions: University of Health Science, S.B.Ü. Bursa Yüksek İhtisas Eğitim ve Araştırma Hastanesi, University of Health Sciences