Biologyarticle2026-08-05

Glechoma hederacea (L.): Phytochemical Profile, Biological Activities and Emerging Perspectives in Oral Health—A Review

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Abstract

Current interest in the use of medicinal plants for the prevention and management of various diseases has increased significantly due to the need to identify effective, safe, and sustainable natural agents. Glechoma hederacea L., a perennial species belonging to the Lamiaceae family, has traditionally been used in European folk medicine for the treatment of respiratory, inflammatory, and digestive disorders. Modern research has highlighted a complex phytochemical profile dominated by phenolic acids, flavonoids, and volatile compounds that have been associated with a variety of biological activities. Experimental studies have reported antioxidant, antimicrobial, anti-inflammatory, and cytoprotective effects. The present review summarizes current data regarding the phytochemical composition and biological properties of Glechoma hederacea, with particular emphasis on its potential applications in oral hygiene products and complementary dental therapy.

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Authors: Alicia-Denisa Bereteu-Costa, Annamária Pallag, Georgiana Ioana Potra Cicalău, Mariana Ganea, Bianca Pașca, Monica Tabita Morar, Gabriela Ciavoi

Institutions: University of Oradea