STABILOMICS: MECHANISTIC ROLE AND TRANSITION TOWARD TRIS (2,4-DI-TERT-BUTYLPHENYL) PHOSPHATE-FREE POLYMERIC FILMSPallab Mandal1*, Priyabrata Pattnaik2, Chandan Sah3, Prasenjit Swain4, Sagar Maharana5

Abstract

This review critically examines the multifunctional role of tris (2,4-di-tert-butylphenyl) phosphate as a secondary antioxidant in polymeric film technology. The paper discusses its molecular stabilization mechanism, synergistic interactions with primary antioxidants, processing behaviour, degradation pathways, migration characteristics, toxicological profile, regulatory considerations and industrial applications. Particular emphasis is placed on the increasing demand for tris (2,4-di-tert-butylphenyl) phosphate -free polymeric films driven by stringent regulatory requirements, sustainability objectives, pharmaceutical and food-contact packaging standards, and advances in non-migratory stabilizer technologies. Current challenges, emerging stabilization strategies and future research directions are also highlighted.