Research Briefs

Medicine · Infectious Diseases

SARS-CoV-2 and COVID-19 Research

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Abstract editorial illustration accompanying the article: Study links updated COVID-19 vaccination with fewer hospital stays in rheumatic disease
Health & Medicine
Moderate evidenceHuman study

Study links updated COVID-19 vaccination with fewer hospital stays in rheumatic disease

This retrospective human cohort study examined 60,980 adults with autoimmune rheumatic conditions who developed COVID-19 between December 2020 and August 2024. Researchers found that vaccinated patients, including those who received an updated 2023–2024 vaccine or a booster, had lower adjusted odds of COVID-19-related hospitalization than patients with no recorded vaccine doses. The study found associations, not proof that vaccination caused the lower risk.

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Abstract editorial illustration accompanying the article: Review examines machine learning for mRNA vaccine safety monitoring
Health & Medicine
High evidenceReview

Review examines machine learning for mRNA vaccine safety monitoring

Researchers systematically reviewed 43 English-language studies on using machine learning and multiple real-world data sources to monitor possible side effects of mRNA vaccines. Some models showed good performance in particular datasets, but the studies differed substantially and direct applications to mRNA vaccine safety were often retrospective or limited. This review describes research methods and potential uses; it does not establish how well these tools work in routine healthcare.

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