Cardiovascular Issues in Pregnancy

Review reports lower preeclampsia risk with some higher-dose vitamin D regimens

A systematic review and network meta-analysis examined statins, metformin, and vitamin D in eight randomized trials involving 4,078 high-risk pregnant women. Some higher-dose vitamin D regimens were associated with lower estimated risks of preeclampsia than placebo, but the evidence was limited, heterogeneous, and rated low certainty.