Zonguldak Bülent Ecevit University

Regional Expression Profiles of Artemin Protein and GFRα3 mRNA During Postnatal Brain Development in Rats

Artemin, a member of the glial cell line-derived neurotrophic factor family, plays important roles in neuronal processes through GDNF family receptor alpha 3 (GFRα3)-mediated signaling. However, the expression patterns of Artemin and GFRα3 during normal postnatal brain developmen...

Modified LIFT via a Lateral Approach Versus Standard LIFT for Transsphincteric Anal Fistula: A Prospective Randomized Study

AIM: To compare the early clinical outcomes of modified ligation of the intersphincteric fistula tract (LIFT) via a lateral approach with those of standard LIFT in patients with magnetic resonance imaging (MRI)-confirmed transsphincteric anal fistula.METHODS: This single-center p...

Hybrid Reinforcement of Carboxymethyl Cellulose Films with Nanocellulose, Bentonite, and Ceramic Industry Waste: Structural, Thermal, and Morphological Characterization

In this study, biodegradable hybrid polymeric films were developed by reinforcing a carboxymethyl cellulose (CMC) matrix with nanocellulose (NC), bentonite, and ground fired ceramic waste recovered from the vitrified ceramic industry. Seven formulations were prepared by the solve...

Impact of Parental Internet Addiction on Children’s Digital Game Addiction Tendency

Objective: The study was conducted to determine the level of internet addiction in parents' lives and to determine the relationship between this situation and children's tendency to be addicted to digital games. Materials and Methods: The study was descriptive, cross-sectional, a...

Barriers to research engagement among medical students in Türkiye: the role of environmental factors

Abstract Background Medical student participation in structured research activities during undergraduate education appears to remain limited and the factors underlying this limited participation are not yet fully understood. Existing validated questionnaires were not suitable for...

Effects of suboccipital or thoracolumbar self-myofascial release added to hamstring stretching on flexibility, spinal mobility, and balance in recreational athletes with hamstring tightness: a three-arm randomized controlled trial

Hamstring stretching and self-myofascial release are commonly used in sports physiotherapy, exercise preparation, and rehabilitation to acutely improve range of motion. However, whether self-myofascial release applied to anatomically remote regions provides additional benefits re...

Panel-Aware Local Background Filtering for Photovoltaic Thermal Anomaly Detection and Automatic Bounding-Box Pre-Annotation

Thermal imaging is widely used for identifying abnormal thermal patterns in photovoltaic (PV) systems. However, complex backgrounds, varying thermal conditions, and environmental factors can reduce the spatial reliability of thermal-anomaly localization, particularly under real o...

Direct versus indirect epiglottis elevation during McGrath MAC videolaryngoscopy: a randomized trial of glottic visualization and the hemodynamic response

Videolaryngoscopy is widely used for tracheal intubation. With Macintosh-geometry videolaryngoscopes such as the McGrath MAC, the epiglottis can be elevated indirectly by placing the blade tip in the vallecula, or directly by advancing it beneath the epiglottis. Their relative ef...

Comparative Evaluation of Large Language Models in Responding to Common Misconceptions Regarding Periodontal Disease and Oral Hygiene

Background/Objective: As large language models (LLMs) are increasingly used to obtain oral health information, their ability to provide accurate and comprehensive responses to patient-focused periodontal questions derived from commonly reported misconceptions is increasingly rele...

Effect of ethyl pyruvate on sleep deprivation-induced cognitive dysfunction in young female rats

Aims: REM sleep deprivation (SD) affects various physiological processes such as learning and memory. The effect of ethyl pyruvate on cognitive functions has been studied in a limited number of studies and has not been investigated on sleep deprivation before. Therefore, the aim...

Competition in Early Childhood: A Systematic Review of Developmental Evidence and a Preliminary Ecological Framework

Competition remains common but under-theorized in early childhood education (ECE), and its developmental implications are fragmented across distinct research traditions. This systematic review synthesized 56 peer-reviewed empirical studies published between 2000 and 2025 and iden...

Gallstone Status Classification Using Adaptive Performance-Diversity Hybrid Ensemble with Pareto-Based Multi-Objective Selection (APDHE-Pareto)

Background/Objectives: Machine-learning models may support gallstone status classification using heterogeneous clinical and body-composition variables; however, ensemble methods often rely on predefined model combinations or arbitrarily weighted performance criteria. This study p...

Population-Level Associations of Diabetes Prevalence and Childhood Overweight with Kidney Cancer Mortality in Türkiye

Background/Objectives: This study aimed to conduct a population-level multivariate analysis of the associations of childhood overweight with kidney cancer mortality and diabetes. Methods: The study used data from the World Health Organization (WHO) and the World Bank for Türkiye...

Triggering receptors expressed on myeloid cells (TREM-1) and TREM-2 as predictors of pathological complete response to neoadjuvant therapy in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is one of the most aggressive subtypes of breast cancer, characterized by early metastasis, high recurrence rates, and limited targeted therapy options. Pathologic complete response (pCR) after neoadjuvant chemotherapy (NACT) is a well-establi...

The role of NLR and MPV in predicting pressure injury development in ICU patients: a retrospective cohort study

Pressure injuries are a common and serious complication in critically ill patients, yet reliable and accessible biomarkers for early risk stratification remain lacking. This study investigated the predictive value of the neutrophil-to-lymphocyte ratio (NLR) and mean platelet volu...

Whole-Life Carbon Governance in Building Regulation: Türkiye and Selected European Regulatory Pathways

Whole-life carbon (WLC) governance is increasingly important to the decarbonization of the built environment, yet its incorporation into building regulation differs across jurisdictions and instrument types. This study examines how WLC governance is represented in Türkiye’s build...

Explainable AI-Based Intrusion Detection Systems for IoT Environments: A Systematic Literature Review

With the rapid proliferation of Internet of Things (IoT) technology today, the number of devices connected to each other through these networks is increasing significantly, and the security risks these devices face from cyberattacks have emerged as a clear problem. Intrusion dete...

Spatio-temporal variations of trihalomethanes and haloacetic acids in water distribution systems with multi-pathway health risk and toxicological assessment

Abstract This study investigated the concentrations of trihalomethanes (THMs) and haloacetic acids (HAAs) across 16 distribution areas in Zonguldak Province (Türkiye). We analyzed their seasonal variations and public health risks in the surface water-supplied Ulutan (UDS) system...

Sustainability and Tourism Growth in the Mediterranean Countries: A Panel Data Analysis

This study investigates the long-term relationships among tourism activity, energy consumption, economic development, and CO2 emissions using panel data for 15 Mediterranean Basin countries observed at 17 time points between 1994 and 2022. Pooled OLS, country fixed-effects, and t...

Integration of military into a democratic system: Morris Janowitz and the failed coup attempt of July 15, 2016

Throughout the history of the Turkish Republic, a series of military coups and memorandums occurred, which deeply impacted political life and interrupted civilian rule up until the failed coup attempt of July 15, 2016. From the early years of the Republic, the decisive power of m...