Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine

The Effect of the MTHFR C677T Genotype Polymorphism on the Efficacy of Folic Acid Treatment for Hyperhomocysteinemia and Cardiovascular Endothelial Function

ABSTRACT Background Cardiovascular disease remains a major public health burden. This study aimed to investigate the effect of the methylenetetrahydrofolate reductase (MTHFR) C677T genotype on folic acid treatment response and cardiovascular endothelial function in patients with...

Risk of intracranial hemorrhage in neonates with hemophilia: a systematic review and meta-analysis

Abstract Background Intracranial hemorrhage (ICH) represents one of the most severe and potentially devastating complications in neonates with hemophilia. Although ICH is well recognized as a major cause of early morbidity and mortality in children with hemophilia, the true incid...

Content characteristics and informational reliability of postoperative pain–related videos on TikTok and Bilibili: a cross-sectional study

Postoperative pain is common and clinically important. Poor pain control may delay recovery, increase readmission risk, contribute to chronic postsurgical pain, and impair long-term quality of life. Meanwhile, patients and caregivers increasingly seek pain-related information on...

Prognostic factors and nomograms predicting overall survival and cancer specific survival for patients with rare histological variant prostate cancer

Our study aimed to develop nomograms to accurately predict the 1-, 3-, and 5-year overall survival (OS) and cancer-specific survival (CSS) of patients with rare histological variant prostate cancer (PCa) based on clinicopathological characteristics. We gathered clinicopathologica...

Spinopelvic alignment changes after unilateral total knee arthroplasty associated with functional recovery

Abstract Background The biomechanical interaction between knee pathology and spine–pelvis alignment in advanced knee osteoarthritis (KOA) has received increasing attention. This study evaluated short-term changes in spinopelvic alignment after unilateral total knee arthroplasty (...