Zhongyuan University of Technology

Nicotinamide Metabolism Constrains Memory CD8 + T Cell Formation Through a Putative HS1BP3‐SIRT1‐FOXO3‐BCL6 Axis

ABSTRACT Memory T cells exhibit long‐term persistence, a defining feature that underpins durable clinical responses to adoptive immunotherapies. The mechanisms that integrate metabolic cues with transcriptional control of memory fate remain undetermined. Here, we identify HS1‐bin...

Stress-State-Dependent Reinforcement of Cement-Stabilized Soil Using Waste Brick Powder and Glass Fiber

Cement-stabilized soil is widely used for ground improvement but suffers from brittleness and low tensile strength. This study investigates combined modification of cement-stabilized soil with waste brick powder (WBP, 5%) and glass fiber (GF, 0–2.0%) to enhance mechanical perform...

Health economic evaluation of discrete event simulation model for treating chronic obstructive pulmonary disease based on traditional chinese medicine syndrome differentiation

Abstract Objectives To evaluate, from a Chinese healthcare system perspective, the cost-utility of three treatment strategies (Western medicine, Traditional Chinese Medicine [TCM], and combined therapy) for stable chronic obstructive pulmonary disease (COPD) using a discrete even...

The influence of self-supporting personality on social anxiety in college students: the serial-mediating roles of attention bias and social problem-solving orientation

Social anxiety is highly prevalent among college students and is associated with impaired academic functioning and long-term social maladjustment. Although prior research has documented the adaptive value of self-supporting personality, the specific cognitive-behavioral mechanism...

The influence of MoS 2 lubricity on the secondary cutting performance of PCD micro-groove textured tools

Micro-textured cutting tools possess unique advantages in reducing cutting forces, lowering chip temperatures, minimizing tool wear, and improving machined surface quality. Nevertheless, the secondary cutting effect induced by micro-textures impairs texture integrity and aggravat...