ZhengZhou Shengda University Of Economics, Business & Management

Charting the Phenotypic Landscape of FBN1 Variants in Marfan Syndrome With Ectopia Lentis Through Extreme Phenotype Sampling

Purpose: Phenotypic heterogeneity is a hallmark of Marfan syndrome (MFS) with ectopia lentis (EL), yet genotype-phenotype correlations for ocular traits remain incompletely understood. This study aimed to identify genomic determinants of extreme ocular phenotypes using a combined...

Genetic algorithm optimized image segmentation for sports motion trajectory extraction motion abnormality detection and potential injury risk indication

This study develops a genetic algorithm (GA)-optimized U-Net framework for sports motion-region segmentation, trajectory extraction, motion anomaly detection, and potential injury-risk indication. The private dataset consisted of 320 sports video clips recorded at 1920 × 1080 res...