Zhengzhou People's Hospital

The gut-ovary axis: how microbial players orchestrate female reproductive health

Ovarian dysfunction—encompassing polycystic ovary syndrome (PCOS), premature ovarian insufficiency (POI), and ovarian aging—poses a significant challenge in reproductive medicine, largely due to the limited availability of etiology-based treatments. Emerging evidence positions th...

Scavenger Receptor Class B Type 1 Mediated Transport Enables Delivery Across Capillarized Liver Sinusoids in Metabolic Dysfunction-Associated Steatohepatitis

Abstract Liver fibrosis in metabolic dysfunction associated steatohepatitis (MASH) lacks effective therapies, in part because therapeutic agents poorly penetrate the capillarized sinusoidal endothelium. As fibrosis progresses, liver sinusoidal endothelial cells (LSECs) become def...

Perforation of the right ventricle and inferior vena cava by bone cement after percutaneous vertebroplasty

Rationale: Percutaneous vertebroplasty (PVP) is widely used to treat vertebral compression fractures. Although it is generally considered a minimally invasive procedure, leakage and systemic migration of polymethylmethacrylate bone cement may rarely occur and can cause potentiall...

Pulmonary embolism in lung cancer: a retrospective exploratory study

Lung cancer is associated with a high risk of venous thromboembolism, and pulmonary embolism (PE) is a critical complication. The synchronous diagnosis of PE at the initial presentation of lung cancer presents diagnostic challenges and affects management. The predictive factors f...

Research progress on multi-mechanism analysis and protection strategies of ovarian aging and fertility decline

Age-related fertility decline is an increasingly important challenge in reproductive medicine, driven largely by progressive ovarian aging. The aging ovary undergoes functional deterioration characterized by reduced ovarian reserve and declining oocyte quality, ultimately limitin...

Tranexamic acid in primary total knee arthroplasty: a systematic review and meta-analysis of blood loss, transfusion, and deep vein thrombosis

Tranexamic acid (TXA) has been widely used in primary total knee arthroplasty (TKA) to reduce perioperative blood loss, but the pooled evidence regarding blood loss, transfusion, and deep vein thrombosis (DVT) remains to be further clarified. The purpose of this meta-analysis was...