Zhengzhou City Hospital

A hybrid memetic algorithm for an energy-aware distributed blocking hybrid flowshop scheduling problem with transportation time

Abstract This study examines the energy-aware distributed blocking hybrid flowshop scheduling problem (DBHFSP-E) considering transportation time. A mathematical programming model is formulated to simultaneously minimize makespan and total energy consumption, and its validity is v...

Multi-omics profiling reveals gene signatures and therapeutic targets in HER2-guided gastric cardia adenocarcinoma patients

Abstract Therapeutic targets for gastric cardia adenocarcinoma (GCA), particularly for HER2-negative patients, are lacking. Here, we conducted multi-omics profiling on 128 GCA patients using mass spectrometry, whole-exome sequencing, RNA-Seq, scRNA-Seq and spatial transcriptomics...