Institution
ZheJiang Institute For Food and Drug Control
Recent research
- Health & MedicineOpen access
Abstract The molecular mechanisms underlying lung metastasis of colorectal cancer (CRC) remain largely elusive, and effective therapeutic agents are still lacking. In this study, we identify levistilide A (LeA) as a potential anti-metastatic agent against CRC lung metastasis. We...
- Health & MedicineOpen access
Reducing sugar content while maintaining palatability remains challenging, particularly when functional ingredients introduce bitterness. However, sweet-bitter interactions are rarely quantified at detection and discrimination thresholds. In this study, we applied a threshold-bas...
- Materials & Energy
Identification of Impurities in Norvancomycin Hydrochloride Drug Substance Using UHPLC‐QTOF‐MS
ABSTRACT Rationale Norvancomycin (NVCM) hydrochloride belongs to a group of glycopeptide antibiotics and exhibits strong effects against Gram‐positive cocci and bacilli. The safety of patients' lives is directly related to the quality of drugs. The impurities play often an import...
- BiologyOpen access
Phenolic acids and flavonoids are major bioactive constituents of Sparganium stoloniferum tubers (SL), yet their spatial organization within this medicinal organ remains insufficiently characterized, limiting understanding of how anatomical structure relates to metabolite distrib...
- Engineering & Technology
IntegratedCRISPR/Cas12a-Based Duplex Detection Platformfor Species Fingerprinting
Abstract Species fingerprinting is crucial to ensure food safety and human health, which requires a rapid, simple, multiplex, and field-deployable detection technique. In response, a lab-on-a-disc microfluidic chip with CRISPR/Cas12a that integrates target preamplification and si...
- Engineering & TechnologyOpen access
Applications of Electronic Nose Technology in Tea Processing: A Comprehensive Review
Tea quality is fundamentally determined by the complex biochemical transformations occurring during manufacturing. Traditional sensory evaluation, while essential, suffers from inherent subjectivity and cannot meet the demands of modern, industrial-scale production monitoring. Th...