Zhejiang Hospital

Two‐ to six‐year outcomes of tunnel technique with connective tissue graft in multiple mandibular anterior recessions

Abstract Background The purpose of this study is to report the 2–6 year outcomes of the tunnel technique with a connective tissue graft (TUN+CTG) in treating multiple Cairo recession type 1 and 2 recessions over a 2–6 year follow‐up, and the influence of CTG exposure on treatment...

The intratumoral microbiome as an emerging hub in cancer pathogenesis and precision oncology

Over the past decade, the number of microbial communities identified within tumors has increased by 400%. Notably, the intratumoral microbiome, which includes bacteria, fungi, viruses, and other microorganisms within tumor tissues, was first discovered more than a century ago. Ba...

Predictive Value of the Systemic Immune-Inflammation Index Combined With the Prognostic Nutritional Index for Flap-Related Complications Following Flap Repair in Patients With Stage Ⅲ and Ⅳ Pressure Injuries

AIM: To investigate the combined predictive value of systemic immune-inflammation index (SII) and prognostic nutritional index (PNI) for postoperative flap-related complications in patients with stage Ⅲ and Ⅳ pressure injuries undergoing flap repair.METHODS: A single-center retro...

Chemotherapy remains effective in ALK-TKI therapy: a retrospective analysis in ALK-positive advanced NSCLC

Tyrosine kinase inhibitors (TKIs) are the standard therapy for advanced non-small cell lung cancer (NSCLC) harboring anaplastic lymphoma kinase (ALK) fusions. However, acquired resistance remains a major challenge, necessitating strategies to prolong therapeutic efficacy. This st...

Integrating nutrition counseling into clinical skills training: a simulation-based interprofessional education program for medical and nursing students

The increasing prevalence of diet-related chronic diseases highlights the urgent need for effective nutrition education in health professions training. This study evaluated a simulation-based interprofessional education (IPE) program designed to enhance nutrition counseling knowl...

Successful surgical retrieval of an intracranial sewing needle retained for more than 45 years since infancy with complete fibrous encapsulation: a case report and literature review

Intracranial sewing needles are an extremely rare neurosurgical condition. Such injuries mostly occur during infancy, with the sewing needle penetrating intracranially through unclosed fontanelles. The clinical manifestations of intracranially retained sewing needles are often in...

Platelet count combined with Child-Turcotte-Pugh score for predicting rebleeding in cirrhotic patients with esophagogastric variceal bleeding

To investigate the predictive value of platelet count (PLT) combined with the Child-Turcotte-Pugh (CTP) score for rebleeding in cirrhotic patients with esophagogastric variceal bleeding (EGVB). This single-center retrospective study included 332 eligible patients selected from 37...

Associations of key diet-quality indexes with trajectory of multimorbidity: a prospective study in the UK Biobank

Dietary patterns have been associated with the morbidity and mortality of individual non-communicable diseases(NCDs). However, the impacts of baseline dietary patterns among the initially healthy population on the progression from healthy to first non-communicable disease (FNCD),...