Zaporizhzhia State Medical and Pharmaceutical University

From Molecular Design to In Vivo Validation: Integrated Efficacy and Safety Profiling of Orotic Acid–1,2,4-Triazole Hybrids with Wound-Healing Activity

Chronic and difficult-to-heal wounds require topical agents that combine reparative activity with favorable local disposition and an acceptable preliminary safety profile. This study evaluated three orotic acid–1,2,4-triazole hybrids (1–3) using an integrated computational and ex...

Molecular epidemiology and management of non-tuberculous mycobacteria isolated from patients in Ukraine, 2022–2024

Non-tuberculous mycobacteria (NTM) are increasingly recognized worldwide as significant causes of chronic pulmonary disease, particularly among individuals with underlying structural lung disorders or immunosuppression. However, data on the epidemiology and clinical management of...

Bacteriological profiling and antimicrobial resistance of combat-related infections: analysis of war wounds from Ukraine during 2024–2025

Combat-related wound infections in the Russo-Ukrainian war pose high morbidity due to the prevalence of multidrug-resistant (MDR) organisms. The aim of the study was to characterize pathogen distribution, antimicrobial resistance (AMR) dynamics, and risk factors (evacuation and s...