Zanjan University of Medical Sciences

Bony labyrinth taxonomic identification and long-term evolution of livestock in the Southwest and Central Asia

Abstract Southwest and Central Asia were pivotal regions for the domestication and dispersal of domestic herbivores. Here we investigate long-term variation in bony labyrinth morphology of domestic bovids (sheep, goats and cattle) across the last 10 000 years. We focused on the o...

Hydrogen-Bonded Poly(vinyl Alcohol)/Tannic Acid/Quercetin Hydrogels for Localized Controlled Drug Delivery

Localized drug delivery systems provide an effective approach for achieving sustained drug release and prolonged drug retention at the target site while minimizing systemic exposure. In this study, physically crosslinked poly(vinyl alcohol)/tannic acid/quercetin (PVA/TA/Que) (PTQ...

Engineering copper ferrite (CuFe2O4) nanosystems for medicine: a comprehensive review from design to biomedical applications

Abstract Biomedical micro/nanosystems are rapidly advancing toward integration of therapeutic and diagnostic nanoscale agents into unified platforms. Engineers still struggle to precisely control multiple functions in biocompatible designs. Copper ferrite (CuFe 2 O 4 ) nanopartic...

Incremental Prognostic Value of CT Indices Derived from Midline Shift and Hematoma Thickness in Acute Subdural Hematoma

Background: In acute subdural hematoma (ASDH), early risk stratification relies heavily on hematoma thickness (HT) and midline shift (MLS). Composite indices derived from these measures have been proposed to better characterize mass effect, but their incremental prognostic value...

The Impact of Life Skills-Based Group Counseling on Sexual Intimacy Among Women of Reproductive Age with Low Sexual Intimacy: A Randomized Controlled Trial

= 0.001). The results suggest that life skills-based group counseling is associated with improved sexual intimacy among women of reproductive age who report low baseline sexual intimacy.

Illness perception in advanced heart failure: a hermeneutic phenomenological study

Heart failure (HF) is a chronic, progressive condition that profoundly affects patients’ physical functioning and their psychological, social, and existential well-being. Beyond its clinical manifestations, patients continuously interpret and assign meaning to their illness, and...

Spontaneous pneumomediastinum secondary to profound weight loss and malnutrition: a case report and review of malnutrition as a primary etiology

Spontaneous pneumomediastinum (SPM) is a rare but significant complication of anorexia nervosa (AN). While historically linked to Valsalva maneuvers, a growing body of evidence implicates severe malnutrition as an associated risk factor, challenging traditional etiologic models....

Plasma p-tau217 as a two-cutoff approach to improve tau-PET screening and trial recruitment in Alzheimer’s disease

Abstract Blood-based biomarkers could broaden access to Alzheimer’s disease diagnostics, but their ability to approximate tau PET, and to address gray-zone results, remains uncertain. We evaluated plasma p-tau217 against tau PET using a harmonized ADNI baseline cohort and an inde...