Yunnan Center for Disease Control And Prevention

A dimeric mRNA vaccine based on key-mutant and KP.3 RBDs induces broad-spectrum immunity and protects mice against JN.1 and XDV challenges

The continued antigenic evolution of SARS-CoV-2 Omicron subvariants has progressively eroded vaccine-elicited protective immunity, driving demand for next-generation candidates that confer broad-spectrum protection against phylogenetically divergent strains. Here we report the de...

ENSO impacts on low wind power events: A long‐term data‐driven analysis using TabNet

Abstract As power systems transition towards decarbonised energy mixes with increasing wind penetration, prolonged low‐wind‐power (LWP) events have emerged as a critical source of adequacy risk. However, a comprehensive analysis of LWP events remains constrained by the scarcity o...

Alignment between undergraduate public health training and workforce competency requirements under medical–public health integration: a dual-perspective cross-sectional study in Yunnan, China

Misalignments may exist between undergraduate public health training and frontline workforce competency requirements under medical–public health integration, particularly in border and multi-ethnic regions. This study assessed this alignment from the combined perspectives of stud...

Identifying factors influencing HIV testing behavior among high-risk elderly men: a mixed-methods study incorporating structural equation modeling and thematic framework

Abstract Background Population ageing has been accompanied by increasing HIV risk among older adults. Timely diagnosis and treatment are essential for improving health outcomes. However, over 65% of HIV cases among older men at elevated risk in China are diagnosed at an advanced...

Long-Term Evidence of ENSO-Driven Rodent Population Dynamics in a Natural Plague Focus of Southwestern China

Climate variability can modulate zoonotic disease risk by altering interactions among wildlife hosts, vectors, and human environments, yet long-term evidence linking large-scale climate oscillations to natural plague systems remains scarce. We investigated the influence of El Niñ...