Yunnan Botanee Biotechnology Group Co.

GPR87 protects UVB-damaged skin by coordinating antioxidant, DNA repair, and anti-inflammatory responses via Nrf2 and PI3K/AKT-NF-κB pathways.

data further showed that GPR87 deficiency aggravated inflammatory responses and cyclobutane pyrimidine dimer (CPD) accumulation while attenuating apoptosis in skin cells. Moreover, GPR87 facilitated CPD clearance by regulating the expression and ubiquitination of XPC, a key compo...