Yuhuangding Hospital

Individualized endobronchial stent therapy for bronchopleural fistulas: a case series

Bronchopleural fistula (BPF) is a rare but serious postoperative complication following lung resection, associated with high morbidity and mortality. Endoscopic stent occlusion has emerged as a minimally invasive treatment option, particularly for patients unsuitable for reoperat...

Diagnosis of pleural mesothelioma via thoracoscopic visceral pleural snare biopsy: a case report

To evaluate the diagnostic efficacy of thoracoscopic visceral pleural snare biopsy for pleural mesothelioma (PM). We present a diagnostically complex case of recurrent right pleural effusion that was ultimately confirmed as PM through thoracoscopic visceral pleural snare biopsy,...

Bag-1 modulates lung ischemia-reperfusion injury by regulating BCL-2 family proteins and IP3R-mediated calcium release

Lung ischemia-reperfusion injury (LIRI) involves dysregulated apoptosis and calcium overload. This study explored the role of molecular chaperone BCL-2-associated athanogene 1 (Bag-1) -1 in LIRI pathogenesis. Using an A549 cell model of glucose deprivation/hypoxia-reoxygenation,...

A machine learning model for predicting early adverse outcomes after surgery in patients with early-onset rectal cancer: a two-center retrospective cohort study

Patients often present at advanced stages of early-onset rectal cancer (EORC), which is becoming more common. Within a year following rectal resection, some patients experience early adverse outcomes (EAO), such as severe complications, recurrence, or death; however, there is cur...

Occult lung adenocarcinoma diagnosed by EBUS-TBNA after pneumothorax resolution in an RA-ILD patient with respiratory failure

RA-ILD is a serious complication of RA. Patients are prone to spontaneous pneumothorax and have a higher risk of lung cancer.Given poor lung function and high risk of pneumothorax recurrence, conventional biopsy is challenging, making diagnosis difficult. A 67-year-old male with...

Estimating individualized gonadotropin starting doses in women with PCOS: a target-driven machine learning model for GnRH-antagonist stimulation

Abstract Background Women with polycystic ovary syndrome (PCOS) are prone to excessive ovarian response and ovarian hyperstimulation syndrome (OHSS) during controlled ovarian stimulation, whereas overly conservative gonadotropin (Gn) dosing reduces oocyte yield and efficiency. Th...