Yoshida Biological Laboratry

Concise Total Synthesis of Streptospherin A

Abstract A practical total synthesis of streptospherin A (1), a cancer stem cell inhibitor, is reported. The key intermediates are obtained stereoselectively in a concise synthesis by a combination of asymmetric allylation and hydroxy-directed stereoselective diboration. These in...

Hydrogel-EmpoweredInterfacial Reactive Hydrogen onCopper Enables Selective Nitrate-To-Ammonia Electrocatalysis

Abstract Precise control of interfacial reactive hydrogen is crucial for improving the selectivity of proton-coupled electron transfer reactions in electrocatalysis. In the nitrate electroreduction to ammonia reaction, a fundamental trade-off is identified for copper (Cu)-based c...