York University

Exploring the Coupling of Pyridines with Dearomatized 4-Alkylpyridines

Abstract We describe approaches to the synthesis of dipyridylmethane scaffolds that have potential use in medicinal chemistry. The general strategy exploits the latent nucleophilicity of 4-alkylpyridines and the inherent electrophilicity of pyridines to achieve metal-free couplin...

Crowd Management in Africa: A Systematic Review of Context-Specific Strategies and Gaps

Since 1991, over 1200 deaths have occurred due to crowd incidents and stampedes across Africa. Children, the elderly, people with disabilities, and women face higher risks due to limited access to resources and support, while young men are more exposed during political and sporti...

Asymptotic linear dependence and ellipse statistics for multivariate two-sample homogeneity test

Statistical depth, which measures the center-outward rank of a given sample with respect to its underlying distribution, has become a popular and powerful tool in nonparametric inference. In this paper, we investigate the use of statistical depth in multivariate two-sample proble...

Understanding spatial and temporal evolution of progressive excavation damage zone in granitic rocks – development of a novel mine-by and laboratory experimental framework at the BedrettoLab

Abstract. The brittle damage around tunnels in the form of spalling is common in massive crystalline rocks subjected to high in-situ stresses. Understanding the short-term development and long-term evolution of the Excavation Damage Zone (EDZ) is particularly important for deep g...

Computation-through-Dynamics Toolkit: Simulated datasets and quality metrics for dynamical models of neural activity

A primary goal of systems neuroscience is to discover how ensembles of neurons transform inputs into goal-directed behavior, a process known as neural computation. A powerful framework for understanding neural computation uses neural dynamics – the rules that govern how neural ac...

Initial Orbit Determination of Low-Earth-Orbiting Objects Using Multi-Site Space-Based Optical Observations

Space Situational Awareness (SSA) is a growing field of study which provides knowledge of Resident Space Objects (RSOs) to help maintain a safe and sustainable space environment around Earth. A primary component of SSA is obtaining Initial Orbit Determinations (IODs) of these obj...

A Bibliometric Analysis of Second Language Assessment Research, 1984–2022

This paper reports the results of a bibliometric analysis of 38 years of second language (L2) assessment research, covering 2,416 articles from 44 Scopus-indexed journals specializing in language assessment, applied linguistics and TESOL, and educational assessment. Using a combi...

Delivery of cardiac rehabilitation through hybrid models and alternative settings by country income classification and decade: Comparisons from the International Council of Cardiovascular Prevention and Rehabilitation’s 2025 Global Audit Update

Objective Cardiac rehabilitation (CR) is an outpatient model of secondary prevention that improves patient outcomes, yet use remains limited. Hybrid/alternative CR addresses these challenges, but global availability, structure, and volumes have not been characterized since the pa...

Organized communities as pre-existing infrastructures of care during the COVID-19 pandemic: A transnational dialogue

This article draws from a community-engaged study of how ordinary people's social justice mobilization during the COVID-19 pandemic in Brazil, Canada, Germany, and Peru placed demands on local and national governments for equitable social policies. It challenges celebratory narra...

Working with goals in youth mental health and substance use service: A review of current practice guidelines and recommendations

Abstract Background Working with goals is a critical yet often overlooked aspect of youth mental health and addictions care, with the potential to strengthen therapeutic relationships, support shared decision‐making, and improve outcomes. Despite its importance, there is no cohes...

Temporal proximity to counseling is associated with longitudinal bedaquiline and antiretroviral therapy adherence in multidrug-resistant tuberculosis and HIV treatment

Background Medication adherence is a persistent challenge in the treatment of multidrug-resistant tuberculosis (MDR-TB) and HIV. Routine counseling notes are an underutilized source of information on patient adherence context. Methods We applied natural language processing (NLP)...

Promoting healthy families: a three‐arm randomized controlled trial of Triple P and Circle of Security–Parenting versus treatment‐as‐usual for families with young children (2–6 years)

BACKGROUND: Parenting programs grounded in social learning (SL) and attachment theory are widely implemented, yet few trials have directly compared their effects across multiple parenting domains in community contexts. This study examined the relative effectiveness of an SL-based...

Status hope: the conceptualisation of the status game

Purpose This study develops a sociological conceptualisation of status hope to explain how the status game is produced and sustained across international marketplaces. It addresses the tension between status pursuit as joyful and autonomous and status as a field-structured strugg...

Bifurcation structure of an SIRS epidemic model with nonlinear incidence rate: Discovery of Hopf-isola phenomena

We study the bifurcation structure of a class of SIRS epidemic models with a nonlinear incidence rate of the form k I p S 1 + ω I q , where the exponents p and q are treated as general parameters. By reducing the model to a planar S - I system, we analyze the existence and degene...

Psychometric Refinement of the Interpretation Inflexibility Task: Assessing Validity and Reliability of Two Short Forms

Interpretation inflexibility, which measures difficulty revising one’s initial interpretation of an ambiguous scenario, has been linked to increased negative affective outcomes. The Interpretation Inflexibility Task (IIT) is a useful tool in measuring inflexibility; however, it f...

The Psychometric Properties of General Mattering Scale, Anti-Mattering Scale, and Fear of Not Mattering Inventory and the Association With Loneliness Among Iranian Students

Mattering is an important psychosocial construct, yet evidence regarding the psychometric properties of mattering measures among Iranian university students remains limited. This study examined the psychometric properties of three mattering scales and their associations with lone...

Wear‐Activated Surface Engineering of Thermoplastic Polyurethane/Graphene Nanoplatelet Nanocomposites for Ice Friction Control

ABSTRACT Graphene‐reinforced thermoplastic polyurethane (TPU) composites offer a promising route for developing multifunctional polymer composites with improved mechanical durability, wear resistance, and surface‐dependent frictional performance. In this study, TPU nanocomposites...

Complex exposure–response relationships between meteorological factors and severe fever with thrombocytopenia syndrome risk

Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease influenced by meteorological factors. This study aimed to characterize the complex exposure–response relationships between multiple meteorological factors and SFTS risk in Anhui Provin...

American Imperialism in the Age of Trump

Donald Trump came to power promising to rejuvenate the US economy and reconfigure global geopolitics to sustain the US-led unipolar order captured in his slogan, Make America Great Again. Economically, he has identified tariffs as a key instrument to punish countries perceived to...

Translating deep learning innovations into clinical medical imaging practice

Deep learning (DL) has fundamentally transformed medical imaging, enabling unprecedented advancements in image quality, automated detection, and diagnostic precision. Despite these technical achievements, a significant translational gap persists between algorithmic development an...