Yokohama Municipal Citizen's Hospital

Feasibility of an exercise intervention for chemotherapy-related fatigue in patients with gynecologic cancer: a randomized controlled trial with multidimensional assessment

Although exercise interventions have shown benefits in several cancer populations, evidence during chemotherapy for gynecologic cancers remains limited. This randomized controlled trial evaluated the feasibility and efficacy of a home-based exercise intervention for cancer-relate...

Evaluation of the UK Myeloma Research Alliance risk profile in transplant‐ineligible multiple myeloma patients treated with novel agents

Summary The heterogeneity of multiple myeloma (MM) significantly impacts treatment outcomes. Myeloma risk profile (MRP), introduced by the UK Myeloma Research Alliance, is a novel prognostic model for patients with transplant‐ineligible newly diagnosed MM (TIE‐NDMM) utilizing eas...

Long-Term Survival Outcomes of Modified-FOLFOXIRI Plus Cetuximab Versus Bevacizumab in RAS / BRAF Wild-Type Metastatic Colorectal Cancer: Final Analysis of the DEEPER Trial

The randomized phase II DEEPER trial (jRCTs061180022) previously reported superior depth of response with modified 5-fluorouracil, leucovorin, oxaliplatin and irinotecan (m-FOLFOXIRI) plus cetuximab versus bevacizumab in patients with RAS wild-type metastatic colorectal cancer (m...

Loss of SATB2 is associated with MUC16 upregulation in the invasive component of colitis-associated colorectal carcinoma

Colitis-associated colorectal carcinoma (CAC) arises in the setting of long-standing inflammatory bowel disease and shows clinicopathological and molecular differences from sporadic colorectal carcinoma. Loss of SATB2 expression is increasingly recognized in a subset of CACs, but...