Yokohama Municipal Citizen's Hospital

Loss of SATB2 is associated with MUC16 upregulation in the invasive component of colitis-associated colorectal carcinoma

Colitis-associated colorectal carcinoma (CAC) arises in the setting of long-standing inflammatory bowel disease and shows clinicopathological and molecular differences from sporadic colorectal carcinoma. Loss of SATB2 expression is increasingly recognized in a subset of CACs, but...