Yeungnam University College

Phase IIa Trial of Locoregional High-Dose Autologous Natural Killer Cell Therapy Combined with Hepatic Arterial Infusion Chemotherapy for Locally Advanced Hepatocellular Carcinoma

PurposeHepatocellular carcinoma (HCC) refractory to locoregional therapies remains a major clinical challenge.This study evaluated the efficacy and safety of locoregional high-dose autologous natural killer (NK) cell therapy combined with hepatic arterial infusion chemotherapy (H...

Breast cancer stem cell metabolism: metabolic plasticity and microenvironmental regulation

Breast cancer stem cells (BCSCs) are a tumorigenic cell population implicated in tumor initiation, therapeutic resistance, metastasis, and disease recurrence. Increasing evidence indicates that metabolic reprogramming is a fundamental feature of BCSC biology, enabling these cells...

Nonarteritic anterior ischemic optic neuropathy after rapid weight loss during semaglutide therapy: a case report

Semaglutide, a glucagon-like peptide-1 receptor agonist, is increasingly used for obesity management; however, concerns have recently emerged regarding potential ocular adverse events, including nonarteritic anterior ischemic optic neuropathy (NAION). Herein, we report a case of...

Shockable rhythm as an independent prognostic factor in patients with non-ST elevation undergoing percutaneous coronary intervention after out-of-hospital cardiac arrest: a registry-based cohort study

BACKGROUND: Although the timing and indications for coronary angiography (CAG) after out-of-hospital cardiac arrest (OHCA) have been widely studied, the characteristics associated with favorable outcomes in patients with non-ST-elevation (non-STE) undergoing percutaneous coronary...

Reconstruction of a 20-cm tibial bone defect after recurrent fracture-related infection using the induced membrane technique and rhBMP-2 augmentation with limited autogenous bone availability: a case report

Reconstruction of a 20-cm tibial bone defect after recurrent fracture-related infection using the induced membrane technique and rhBMP-2 augmentation with limited autogenous bone availability: a case report

Impact of a prolonged nationwide residents’ strike on acute ischemic stroke care in a metropolitan city

Abstract BackgroundAcute ischemic stroke (AIS) requires timely management in both prehospital and in-hospital phases to optimize outcomes. In 2024, South Korea experienced a prolonged nationwide residents’ strike that disrupted the healthcare system, potentially affecting AIS man...

Dynamics, function, and regulation of mammary stem cells in development and disease

Understanding the heterogeneity of mammary epithelial cells and their contributions to postnatal development and regeneration is of great importance. Recent advances have defined the intrinsic complexity of the mammary epithelium, its stromal interactions, and the ontogeny of adu...