Yangpu Hospital of Tongji University

METTL3-mediated m6A modification of TP73-AS1 enhances HCC progression by activating Wnt/β-catenin signaling

Long noncoding RNAs (lncRNAs) play key roles in the onset and progression of hepatocellular carcinoma (HCC). Tumor protein 73 antisense RNA 1 (TP73-AS1), a recently identified lncRNA, has been implicated in cancer occurrence, drug resistance, and prognosis; however, its function...

Risk factors for acute ischemic stroke of small vessel occlusion in elderly patients with cerebral small vessel disease and establishment of a prediction model

Cerebral small vessel disease (CSVD) accounts for 25% of ischemic stroke causes, yet risk factors for acute ischemic stroke (AIS) in elderly CSVD patients remain unclear. This study aimed to identify these risk factors and establish a prediction model. This single-center retrospe...

From intravascular imaging to adaptive vascular care: intelligent photonics and digital twins in panvascular disease

Panvascular diseases (PVDs) stand as the leading cause of global mortality, necessitating a paradigm shift from local anatomical repair to the systemic restoration of vascular homeostasis. While intravascular optical imaging has revolutionized diagnosis, it remains a passive obse...

Institutional complexity and entrepreneurial work in grassroots cultural heritage: Evidence from Hanfu entrepreneurship in China

Abstract Cultural heritage entrepreneurship (CHE) often requires entrepreneurs to reconcile authenticity claims with commercial imperatives. This challenge is especially pronounced in grassroots heritage revivals where heritage meanings are contested and cultural authority is une...