Yanbian University

RPS27L Maintains Nucleolar Homeostasis to Regulate Proliferation and Differentiation of Bovine Skeletal Muscle Satellite Cells

The in vitro expansion of bovine skeletal muscle satellite cells (SMSCs) is critical for cultured meat production. Here, we investigated the role of ribosomal protein S27-like (RPS27L) in regulating satellite cell proliferation and differentiation. RPS27L knockdown markedly inhib...

Anti-Inflammatory Effects of Ginsenosides: Molecular Mechanisms and Network Pharmacology Analysis

Inflammation is a pathological process central to many chronic diseases. Conventional anti-inflammatories, including NSAIDs and corticosteroids, are limited by adverse effects and suboptimal efficacy with long-term use. Ginsenosides from Panax ginseng have emerged as promising mu...

Glycolytic reprogramming and the EMT drive cervical cancer progression via the NQO1/HIF1α-SIX1 axis

Cervical cancer aggressiveness and therapeutic resistance are driven by metabolic reprogramming and redox imbalance. Within this context, NAD(P)H: quinone oxidoreductase 1 (NQO1), a critical regulator of cellular redox homeostasis and energy metabolism, is highly expressed in sev...