Yan'an University

Genome-Wide Identification and Stage-Dependent Analysis of Odorant-Binding Protein and Chemosensory Protein Genes in the Summer Fruit Tortrix Moth, Adoxophyes orana (Lepidoptera: Tortricidae)

The summer tortrix fruit moth, Adoxophyes orana, is a major fruit trees pest in Asia and Europe, which rolls leaves for food and generate silk nets to avoid prey by natural enemies. As a polyphagous species whose host plants cover more than 30 species, it relies on the olfactory...

Some Results on Spectra and Energy of Edge-Connectivity Matrices of Graphs

The spectrum of a matrix refers to the multiset of its eigenvalues, and its spectral radius refers to the maximum absolute value of its eigenvalues. The energy of a matrix is defined as the sum of the absolute values of all its eigenvalues. For a connected graph [Formula: see tex...

The endothelial activation and stress index (EASIX) as a prognostic marker in patients undergoing cardiac surgery

Cardiopulmonary bypass (CPB)-assisted cardiac surgery is associated with endothelial stress, systemic inflammation, and postoperative organ injury. The Endothelial Activation and Stress Index (EASIX), calculated from lactate dehydrogenase, serum creatinine, and platelet count, ma...

ZC3H13-Mediated m 6 A Modification of TRIM16 Suppresses EndMT and Atherosclerosis by Destabilizing Ang2 and Inhibiting the TLR4/NLRP3 Pathway

The RNA methyltransferase zinc finger CCCH-type containing protein 13 (ZC3H13) is downregulated in atherosclerosis (AS), but its functional mechanism remains unclear. Endothelial-mesenchymal transition (EndMT) is a core pathological driver of endothelial dysfunction in AS. This s...

Integrated Multi-Omics Profiling of Thymoma Identifies Subtype-Specific Remodeling and Myasthenia Gravis-Associated Targets

Abstract Thymoma is a rare thymic epithelial tumor strongly associated with myasthenia gravis (MG), yet the tumor intrinsic molecular states underlying this link remain unclear. Here, we profiled paired thymoma and distant nontumorous thymic tissues using untargeted metabolomics,...

Explainable machine learning model based on cardiac CT angiography for predicting functional improvement after atrial fibrillation ablation: a multicenter study

Radiofrequency ablation is an established therapy for atrial fibrillation (AF), but outcomes are heterogeneous in patients with concomitant heart failure (HF). Therefore, we aimed to develop an explainable machine learning (ML) model based on cardiac CT angiography (CTA) for pred...

Machine-Learning-Driven Performance Optimization of Nano-Modified Construction Materials: A Bibliometric Analysis and Systematic Review

Nanomaterials improve the fresh-state behavior, mechanical performance, durability, and multifunctionality of construction materials through packing and filling, nucleation, interfacial regulation, crack bridging, transport-barrier effects, and functional responses. These benefit...

Energy-aware hybrid artificial bee colony and reinforcement learning for multi-objective task scheduling in green cloud–fog industrial IoT systems

Efficient task scheduling in Cloud–Fog computing environments remains a critical challenge in Industrial Internet of Things (IIoT) systems due to the conflicting requirements of energy efficiency, latency reduction, and Quality of Service (QoS) assurance. This paper proposes an E...

Analysis of Soil Quality Characteristics and Driving Factors of Micro-Landforms in Loess Hilly Areas

To assess soil quality in micro-topographic units of loess hilly regions, this study selected five typical micro-landforms (shallow gully, collapse, steep slope, gentle terrace, cut gully) along with the original slope as a control. We measured 23 indicators covering soil physico...

Clinical efficacy and precision of computer-assisted navigation combined with unilateral biportal endoscopy in lumbar spinal stenosis

The aim of this study was to assess the clinical efficacy, precision, and safety of computer-assisted navigation combined with unilateral biportal endoscopy (UBE) in the treatment of lumbar spinal stenosis (LSS). A retrospective analysis was conducted on the clinical data of 99 p...

Fungal extracellular vesicles reshape Lactobacillus rhamnosus vesicles to enhance lysosomal homeostasis and resolve intestinal inflammation

Extracellular vesicles (EVs) are emerging mediators of intercellular and interkingdom communication. While bacterial EVs directly modulate host health, whether exogenous vesicles can reprogram gut microbial vesiculation and bioactivity remains unclear. Using a defined in vitro co...

Apolipoprotein D3 is required for long‐chain cuticular hydrocarbon accumulation and water retention in Acyrthosiphon pisum

BACKGROUND: The pea aphid, Acyrthosiphon pisum, is a damaging phloem-feeding pest of legume crops, and RNA interference (RNAi)-based targeting of stress-adaptation genes offers a promising route for target-specific pest management. Apolipoprotein D (ApoD) proteins are putative li...

A Semi-Analytical Solution for Interpretation of Hydro-Mechanical Responses of Cylindrical Cavity Expansion in Unsaturated Structural Loess

The cavity expansion solution for loess is absent because the existing elastoplastic models fail to model the sophisticated behaviors of unsaturated loess as a classic axisymmetric boundary-value problem. This paper develops a novel solution for cavity expansion in unsaturated st...

A High‐Voltage Mild Alkaline Zinc‐Iodine Battery Enabled by Tailored Redox Couples

ABSTRACT Aqueous zinc–iodine batteries are promising energy storage systems. However, the voltage is limited in mild acidic electrolytes, while alkaline electrolytes lead to severe passivation at both electrodes. Herein, we optimize zinc–iodine battery systems by tailoring the re...

N-Acetylcysteine Attacks Phenoloxidase to Inhibit Insect Melanization and Boost Fungal Virulence

The prophenoloxidase (PPO) melanization cascade is a cornerstone of insect humoral immunity against fungal pathogens, yet its direct fungicidal mechanism remains undefined, and strategies to safely manipulate this pathway for biological control are lacking. Here, we demonstrate t...

Traditional Chinese Herbal Formula YA3D3 Ameliorates Alzheimer's Disease-Like Pathology and Cognitive Impairment in APP/PS1 Transgenic Mice.

therapeutic efficacy of YA3D3 and the up-regulation of ATG14 requires further confirmation.In addition，this study only verifies the expression regulation of autophagy-related molecules and does not confirm the enhancement of autophagy flux.

From chemical oscillators to biological synchrony: a programmable reaction-diffusion model for studying signal coordination in cardiomyocyte networks

Abstract The self-organization of asynchronous rhythms into synchronized beating in in vitro cardiomyocyte networks is a fundamental problem in systems biology research. Inspired by the dynamics of chemical oscillators, this paper presents a programmable model framework based on...

Nonlinear association between maternal depressive symptoms and overreactive parenting among preschool children: a cross-sectional study

Maternal depressive symptoms (MDS) have been associated with negative parenting practices. However, research examining the specific pattern between MDS and overreactive parenting remains limited. Our objective was to comprehensively assess the association between MDS and overreac...

Fingolimod overcomes cisplatin resistance in esophageal squamous cell carcinoma by targeting NUP54 to disrupt homologous recombination repair

Cisplatin resistance is a major obstacle in the treatment of esophageal squamous cell carcinoma (ESCC). To address this challenge, we screened a U.S. Food and Drug Administration (FDA)-approved drug library and identified fingolimod, an immunomodulatory agent, as a potent inhibit...