Yamaguchi University

Relationship between initial dose, dose intensity, and survival in unresectable pancreatic cancer treated with nanoliposomal irinotecan, fluorouracil, and folinic acid

Abstract While nanoliposomal irinotecan with fluorouracil and folinic acid (NFF) is a standard second-line regimen for unresectable pancreatic cancer (uPC) after gemcitabine-based therapy, the effects of initial dosing and relative dose intensity (RDI) in routine practice are unc...

A Tert ‐Alkyl Terephthalate Derivative as a Universal Degradable Unit for Condensation Polymers

ABSTRACT Incorporating cleavable triggers into the backbones of parent polymers enables programmed degradation, offering a pathway to chemically recyclable plastics. Although various triggers have been reported to date, simple esters bearing a C─O bond cleavable by photocatalytic...

An intractable case of primary intra-axial central nervous system Rosai–Dorfman disease

Background: Rosai–Dorfman disease (RDD) is a rare histiocytic disorder with a typically benign clinical course. However, isolated involvement of the central nervous system (CNS), particularly in the form of primary intra-axial disease, is exceedingly rare. We report an intractabl...