Yamagata Prefectural Central Hospital

A multicenter phase II trial of ramucirumab plus irinotecan for early recurrence of gastric cancer during or after adjuvant chemotherapy with docetaxel plus S-1 therapy: the RAMIEL trial (OGSG1901)

Abstract Background There is currently no established chemotherapy regimen for early recurrence of pathological stage III gastric cancer (GC) following adjuvant chemotherapy with docetaxel plus S-1 (DS) after D2 gastrectomy. We aimed to evaluate the efficacy and safety of ramucir...

Phage treatment reduces multidrug resistant Pseudomonas aeruginosa biofilms and sewage pseudomonads

Untreated wastewater can retain antimicrobial-resistant bacteria, yet phage performance is inferred from simplified host systems. We evaluated genome-resolved lytic phage ɸPRS-1 against Pseudomonas aeruginosa PAO1 in planktonic and single-strain biofilm assays, wastewater-derived...