Xinxiang University

Watermelon vine as dual-functional additive in ecological porous concrete

Ecological porous concrete (EPC) is constrained by a persistent trade-off: the dense cementitious matrix required for strength reduces porosity and generates a highly alkaline pore environment (pH > 11) inimical to plant growth. To address this, the present study investigates wat...

Augmenting antitumor immunity in colon cancer via GSDMD-mediated pyroptosis induced by an attenuated Salmonella delivery system

As a major gastrointestinal malignancy, colon cancer (CC) demands more effective therapies. Gene therapy is an emerging promising strategy, and pyroptosis, a novel lytic cell death form, serves as a vital antitumor target, with Gasdermin D (GSDMD)—a key pore-forming protein in py...

Structure-Guided Hybrid GCN−Transformer Framework for Enzyme Optimal pH Prediction

Abstract Accurate prediction of enzyme optimal pH (pHopt) is fundamental to biocatalyst engineering, pharmaceutical development, and process optimization, yet developing a reliable computational method remains challenging. To address this limitation, we present trPHopt, which is...

An AD detection system using topic enhancement and dynamic differential privacy for intelligent elderly care

To address the challenges of low detection accuracy and high privacy leakage risk in Alzheimer’s disease (AD) detection for intelligent elderly care systems, this paper proposes ADDETECTOR, an AD detection system based on topic enhancement and dynamic differential privacy. The sy...

Evolutionary Game Analysis and Capability Reconstruction of Coal Mine Disaster Emergency Governance Oriented Toward Collaborative Resilience

Coal mine disaster emergency governance requires sustained coordination among regulators, mining enterprises, and professional rescue forces. This study develops a budget-closed tripartite evolutionary game in which subsidy/support outflows and penalty-revenue incidence are repre...

Distinguishing Contemporaneous Rule Recovery from Financial Risk Forecasting in Higher Education Institutions: A Controlled Synthetic-Panel Experiment

High classification performance in financial-risk early-warning research may reflect recovery of a constructed contemporaneous rating rule rather than prediction of an independent future outcome. This study distinguishes these two forms of evidence through a controlled synthetic-...

Developmental Relations Between Oppositional Defiant Disorder and Depression in Childhood: A Symptom Level Perspective

Background Oppositional defiant disorder (ODD) has substantial comorbidity with depression. However, their comorbidity at the symptom level, including potential gender differences, is currently underspecified. This study aimed to explore the comorbidity network of ODD and depress...