Xi'an Medical University

The effect of social support on physical activity of hemodialysis patients : the chain mediating role of exercise self-efficacy and barriers to exercise benefits

Abstract Background Maintenance hemodialysis patients exhibit low physical activity, which is associated with sarcopenia, increased risk of cardiovascular events, and elevated all-cause mortality. Social support is an important resource for promoting healthy behaviors. But the me...

Orthopedic Biomaterials in the Clinical Reconstruction of Osteoporotic Atlantoaxial Injuries: A Review

Background: Aging of the population increases the incidence of osteoporosis with atlantoaxial instability. Poor bone microarchitecture causes high rates of screw loosening, implant failure, and revision surgery, which remains a critical challenge for upper cervical surgery. Tradi...

Lysosome‐Targeted Self‐Adjuvanting Ammonia Nanogenerator Potentiates Hepatocellular Carcinoma Immunotherapy via Ammonia Death

ABSTRACT Ammonia death is a recently identified form of regulated cell death with unique molecular mechanisms and prominent anticancer activity. Nevertheless, its efficacy is severely restricted by the absence of tumor‐targeted ammonia delivery vehicles and poorly defined immunog...

An ioversol-enhanced micro-CT workflow for hematoma visualization and preoperative localization in a murine autologous blood model of intracerebral hemorrhage

Abstract Autologous blood injection produces a discrete striatal clot in mice, but the hematoma is usually confirmed only after brain removal and sectioning, making craniotomy planning difficult for evacuation studies. To address this limitation, we mixed freshly collected autolo...

The bidirectional Thymus-Gut Axis: redefining central tolerance in digestive autoimmunity

Digestive autoimmune diseases impose an escalating global burden, largely because current therapies predominantly target downstream inflammation rather than primordial defects in immune tolerance. The thymus establishes central tolerance through stringent T cell selection and thy...