Xi'an Medical College

MST1 inhibition mitigates fat deposition in rotator cuff tears by modulating the WNT/β-catenin pathway

PURPOSE: Fatty infiltration of the supraspinatus muscle following rotator cuff tear (RCT) is a major pathological factor leading to poor functional outcomes, yet effective treatments are lacking. The kinase mammalian Sterile 20-like kinase 1 (MST1) has been implicated in metaboli...