Xiamen Medical College

Remnant cholesterol inflammatory index and new-onset Fried-phenotype frailty in middle-aged and older Chinese adults: a prospective CHARLS cohort study

Abstract Background Composite indices combining remnant cholesterol with high-sensitivity C-reactive protein (hs-CRP) may capture frailty-relevant inflammatory–lipid risk. The remnant cholesterol inflammatory index (RCII) has been linked to cardiometabolic disease and Frailty-Ind...

Puerarin Attenuates Binge Ethanol-Induced Cortical Neurotoxicity in Association with AKT/mTOR Signaling and Autophagy-Related Responses

, has demonstrated neuroprotective potential in multiple neurological disorders; however, its effects on ethanol (EtOH)-induced cortical injury and the associated molecular responses remain incompletely understood. In the present study, network pharmacology was combined with in v...