Xerox (France)

Detection and Potency Classification of Pre- and Pro-Haptens Using the SENS-IS Assay: The Role of Metabolically Competent Reconstructed Skin

Skin sensitisation assessment increasingly relies on non-animal methods, yet the detection and characterisation of substances requiring metabolic activation, such as pre- and pro-haptens, remain challenging for several existing new approach methodologies (NAMs). The present study...