Wuhan Puai Hospital

Combined metabolomics and network pharmacology explore the protective mechanism of bornyl acetate against cognitive impairment in chronic sleep-deprived mice

Abstract Chronic sleep deprivation (CSD) is currently a serious global public health concern, and CSD induces numerous diseases, including cognitive impairment. Bornyl acetate (BA) possesses a brilliant anti-inflammatory activity and plays a favorable role in neuroinflammation. T...

Prevalence and geographic variation of enteric pathogens among asymptomatic individuals in China: a nationwide, cross-sectional, multiplex molecular survey

The increasing use of multiplex molecular assays has improved the detection of enteric pathogens, but baseline carriage in asymptomatic populations remains poorly characterized, complicating the interpretation of positive test results. We aimed to investigate the prevalence and g...

Clinical outcomes of combined hepatic arterial infusion chemotherapy with targeted or immunotherapy in advanced hepatocellular carcinoma

This retrospective study aimed to evaluate the efficacy and safety of combining hepatic arterial infusion chemotherapy (HAIC) with tyrosine kinase inhibitors (TKIs) or immune checkpoint inhibitors (ICIs) versus HAIC alone for the treatment of advanced hepatocellular carcinoma (HC...