Wuhan No.1 Hospital

Early-life exposure to polypropylene microplastics and DEHP induces ASD-relevant neurodevelopmental alterations involving mTOR-regulated autophagy impairment

The health risks of polypropylene plastic, a major food-grade polymer, are often underestimated. Current evidence indicates that infants and young children may ingest millions of polypropylene microplastic particles (PP-MPs) daily, accompanied by co-exposure to di(2-ethylhexyl) p...

Associations of outdoor artificial light at night with type 2 diabetes and metabolic syndrome among Chinese adults

This study investigated the associations between outdoor artificial light at night (ALAN) and type 2 diabetes (T2DM) and metabolic syndrome (MetS) and aimed to characterize the dose-response relationships and potential exposure thresholds. This cross-sectional study included 57,8...

Surgical strategies for external auditory canal cholesteatoma based on the He staging system: a retrospective study

PURPOSE: To investigate individualized surgical treatment strategies and clinical management experience for external auditory canal cholesteatoma (EACC) based on the He staging system. METHODS: Clinical data from 59 patients (61 ears) with EACC who underwent surgical treatment at...