Worcester State University

Re-evaluating the Digital Transformation of Local Government Institutions to Build SMART Local Governance in Bangladesh: A Study on Municipalities

Purpose This article examines the ongoing efforts and challenges of digitising local government institutions in Bangladesh, focusing specifically on Paurashava (municipalities). Methods This was an applied cross-sectional study that collected data from eight municipalities from f...

Embryo–Fetal Development and Maternal–Fetal Exposure of the Von Willebrand Factor Binding Aptamer Rondaptivon Pegol (BT200) in Rabbits

Rondaptivon pegol (BT200) is a PEGylated RNA aptamer that prolongs von Willebrand factor (VWF) and factor VIII half-lives in patients with hemophilia A and von Willebrand disease (VWD) type 2B. Embryo–fetal safety is particularly relevant given the disproportionate disease burden...

Mitochondrial subpopulations in oocytes and cumulus cells exhibit distinct age-associated changes and selective plasticity in response to NMN supplementation

Abstract Background Mitochondrial dysfunction is a leading contributor to the decline in oocyte quality associated with maternal aging. Prior investigations of mitochondrial function in the ovarian follicle have largely treated the mitochondrial pool as a homogeneous population,...