Woosuk University

Effects of Chondroitin Sulfate on Joint Symptoms and Physical Function in Adults with Mild Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Trial

Background/Objectives: Although chondroitin sulfate (CS) is commonly used for knee osteoarthritis (OA), evidence regarding its effects on joint symptoms and physical function remains inconsistent. This study aimed to evaluate the effects of CS supplementation on joint symptoms an...

Association of Zinc Supplementation with Recombinant Protein Recovery and Crystallization

Reproducible production of stable recombinant proteins is essential for biochemical and structural studies, but conventional optimization may be insufficient when constrained by protein-specific requirements.In this study, we investigated batch-to-batch variation in the recombina...

Protective Potentials of Natural Products Against Vascular Dementia: A Comprehensive Review of Experimental Studies

ABSTRACT Vascular dementia (VaD), accounting for up to 20% of dementia cases globally, is primarily driven by chronic cerebral hypoperfusion (CCH), which leads to progressive cognitive impairment. Despite the increasing prevalence of VaD, effective treatments remain limited. Natu...

Biased Random Walk on a Multiscale Interactome Prioritizes Candidate Herbs and Active Constituents for Psoriatic Arthritis

Psoriatic arthritis (PsA) is a chronic immune-mediated arthropathy characterized by synovitis, enthesitis, and coupled bone erosion and pathological new-bone formation. Although biologics have improved outcomes, incomplete or lost response and safety constraints motivate the sear...

Transporter Interactionsof Methoxyflavones and Their In Vivo PharmacokineticImplications

Abstract Flavonoids are widely consumed dietary polyphenols that modulate drug disposition via membrane transporters. Increasing attention has been paid to methoxyflavones (MeO-FLVs) because methoxylation can increase membrane permeability and metabolic stability, potentially ele...