Women's College Hospital

Evaluating an e-learning curriculum for forensic nurse examiners on providing supports to persons sex trafficked

Sex trafficking is a pervasive health and human rights issue, disproportionately experienced by structurally marginalized women and girls, in Canada and globally. Specialized forensic nurses are well positioned to respond to sex trafficking by offering needed supports, however, c...

Topical Finasteride 0.25% Solution for Female Pattern Hair Loss (FPHL) in Postmenopausal Women: A 52‐Week Retrospective Observational Study

BACKGROUND: Female pattern hair loss (FPHL), characterized by progressive follicular miniaturization, is the most common cause of hair thinning in women and increases in prevalence after menopause. While topical minoxidil is approved for FPHL, clinical response is variable. Oral...

Screening for Early Endometriosis Detection (SEED): Co-development of a Symptom-Based Screening Measure for Canadian Young Adults in Primary Care

Background Many Canadians experience prolonged pain, uncertainty, and stigma before receiving an endometriosis diagnosis, with delays averaging 11 years from symptom onset. Endometriosis, defined by the presence of endometrial-like tissue outside the uterine cavity, impacts 10% o...

Cutaneous Adverse Events Associated with Semaglutide, Liraglutide and Tirzepatide: A Systematic Review

Background/Objectives: Incretin-based therapies, including glucagon like peptide-1 receptor agonists (GLP-1 RAs) and glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 RAs, are increasingly prescribed for obesity, leading to greater recognition of associated dermatological...

Trends in Dispensing of Opioids and Benzodiazepines Among Older Adults Admitted for an Acute Hip Fracture Between 2008 and 2024 in Ontario, Canada

INTRODUCTION: Opioids and benzodiazepines (BZDs) are commonly prescribed for managing pain, anxiety, and sleep-related problems following a hip fracture. Both opioids and BZDs carry risks of persistent dependence, falls, and mortality with long-term use. Despite these risks, Cana...

Gender disparities in leadership of methodological research in health science

Objectives Gender disparities in methodological studies are largely unexplored. We aimed to examine gender representation between first and last authorship positions in methodological research in health science. Methods We searched for methodological articles as part of a large s...

Trends in opioid containing drug seizures described as pills between 2020 and 2024 in Canada

People who use drugs may access prescription opioids from unregulated markets to avoid fentanyl and lower toxicity risk, though concerns regarding counterfeit pills have emerged. To better understand the composition of pills that may be circulating in the unregulated drug supply,...

Adipocytes as a Mechanistic Link Between Incretin-Based Therapies and Hair Loss

The physiological effects of glucagon-like peptide-1 receptor agonists (GLP-1RAs) and dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1RAs extend beyond glucose metabolism and body weight regulation. Accumulating clinical evidence has highlighted an association betwee...

Sex & Gender Science: integrating the social with the biological

Abstract For decades, researchers have largely studied aspects of sex and gender separately; the former as a basic science and the latter as a social construct with real world consequences, including health inequities. In recent years, as our collective understanding of how the b...

Trends in HIV prevention outcomes among Northern and Indigenous adolescents: A repeated cross-sectional study of arts-based sexual health workshops in the Northwest Territories, Canada

Background: Arts-based sexual health workshops may improve adolescent sexual health, yet limited studies have evaluated outcome trends over time. This study examined HIV prevention outcomes before and after school-based workshop participation among adolescents in the Northwest Te...

Women’s and health professionals’ needs and preferences informing the updated IMS recommendations

OBJECTIVE: This study aimed to identify and compare the priorities for content and accompanying resources of midlife women (MW) and health professionals (HPs) to inform the updated International Menopause Society (IMS) recommendations. METHOD: Two online multi-language surveys wi...

Association between exposure to air pollution and age at natural menopause: The Study of Women's Health Across the Nation.

CONTEXT: Air pollution is a recognized risk factor for women's subfertility, yet its association with the timing of natural menopause remains understudied. OBJECTIVES: To examine the association between exposure to ambient air pollution and age at natural menopause (ANM). DESIGN...

Considerations for optimal team-based rheumatology care: a qualitative study exploring the experiences of rheumatology health professionals

Interdisciplinary team-based rheumatology care models are a promising solution for improving access to high quality, equitable care for people with rheumatic and musculoskeletal disorders. There is limited understanding on health professionals’ perspectives on their needs to deli...

Janus kinase inhibitors combined with 308‐nm excimer laser for vitiligo: A systematic review

The data that supports the findings of this study are available in the external repository (https://data.mendeley.com/datasets/6rh8dcvmfv/1) of this article.

Team-Based Outpatient Rheumatology Care: A Scoping Review of Terminology, Team Composition, and Impact on Advancing the Quintuple Aim

Objectives Team-based models of rheumatology care, in which rheumatologists and interdisciplinary healthcare professionals (IHPs) collaborate in care delivery, are increasingly recognized to improve outcomes across all domains of the Quintuple Aim (population health, patient expe...

Icotrokinra (ICO), a Novel Targeted Oral Peptide, in Patients (Pts) with Psoriatic Disease: Exploratory Assessments from a Phase 2 Psoriasis (PsO) Study Informing a Phase 3 Clinical Program in Psoriatic Arthritis (PsA)

Objectives PsA affects ~20-30% of patients with PsO, causing articular inflammation and impaired quality of life. ICO, a novel targeted oral peptide that binds IL-23 receptor, showed greater clinical response rates vs placebo and a favorable safety profile in moderate-to-severe p...

Sex Disparities in Clinical Need, Willingness, and Surgeon Recommendations for Total Knee Arthroplasty

Objectives Sex disparities exist in the receipt of total knee arthroplasty (TKA) for osteoarthritis (OA), with females disproportionately less likely to undergo surgery. Understanding the reasons for this gap is critical for equitable health care delivery. Lower willingness to un...