Women's and Children's Health Network

A bone histological approach to distinguish periprosthetic joint infection from aseptic osteolysis in revision joint replacement

Aims Accurate differentiation between periprosthetic joint infection (PJI) and aseptic osteolysis (AO) remains a major clinical challenge in revision joint arthroplasty. We examined bone biopsies for alterations in bone matrix integrity and the osteocyte lacunocanalicular network...