Wirral University Teaching Hospital NHS Foundation Trust

The Cost of the Cure: Antibiotic Exposure as a Risk Factor for Irritable Bowel Syndrome

The intricate interplay between the gut microbiome and the enteric nervous system remains a paramount focus in understanding the multifactorial pathogenesis of disorders of gut–brain interaction (DGBI), most notably irritable bowel syndrome (IBS). While the clinical entity of pos...

Beyond the biopsy: the new era of non-invasive staging and biomarkers in colorectal cancer

Colorectal cancer (CRC) management is increasingly challenged by shifting demographics, notably the rise in aggressive early-onset CRC, and the limitations of conventional anatomical staging. This comprehensive review explores the paradigm shift toward noninvasive and minimally i...