Western University of Health Sciences

Approved Medications for Substance Use Disorders: An Umbrella Review of Systematic Reviews and Completed Phase 3 Randomized Controlled Trials

This umbrella review of systematic reviews, meta-analyses, and completed phase 3 randomized controlled trials (RCTs) over the past 10 years covers approved pharmacological treatments for substance use disorders (SUD) worldwide, providing clinicians and researchers with a detailed...

Systematic review and meta-analysis of delta large-channel endoscopy in spinal decompression

Delta large-channel endoscopy (DCE) is a novel approach to decompressing spinal nerves that expands the working channel of endoscopic approaches. The goal of this systematic review and meta-analysis was to assess the current literature and compare surgical and clinical outcomes b...

Body Composition and Physical Activity are Associated With Prediabetes in Childhood, Adolescent, and Young Adult Cancer and Hematopoietic Cell Transplantation Survivors

ABSTRACT Survivors of childhood, adolescent, and young adult (CAYA) cancer and hematopoietic cell transplantation have an excess risk of prediabetes and cardiovascular disease. Though not well characterized among CAYA survivors, cancer‐directed therapies may alter body compositio...

Literature Review on HIV-Mtb Coinfection and Stroke Risk

Tuberculosis (TB) is a leading global cause of infectious disease. Growing evidence suggests that TB significantly increases the risk of comorbidity in HIV+ patients, particularly acute ischemic stroke (AIS). Prognosis is often poor, highlighting the need for early prevention and...

Reverse-engineering an expired patent: Characterization of a previously undefined probiotic consortium suggests possible modes of action in broiler chickens

In this study, we characterized the taxonomic composition of a previously patented but uncharacterized mucosal competitive exclusion (MCE) product to identify previously unrecognized bacterial strains and genes that may have contributed to the efficacy of this product. By compari...

APRN education plus professional development focus on leadership roles and responsibilities

ABSTRACT: The collection of papers featured in the special issue highlights educational strategies for preparing APRN students for practice, academic partnerships to improve DNP student experiences, examining NP student mentors' practice output, and professional roles expected of...

Cysteine Adsorbedon Gold Foils with Varying SurfaceChemistries: A ToF-SIMS Study

Abstract Cysteine adsorption on nanostructured gold surfaces is essential for applications in biosensing and nanotechnology, yet studying its interaction with gold nanoparticles is limited by their complex and inaccessible surface chemistries. To address this, we investigated cys...

Examining relationships between sensory processing sensitivity (SPS), physical activity context preferences, and physical activity self-efficacy in undergraduate students

Objective Although regular physical activity (PA) enhances health, university environments often contribute to substantial PA declines for students. This cross-sectional study investigated relationships between Sensory Processing Sensitivity (SPS), a personality trait amplifying...