Westchester Medical Center

Hypertension Management in Breastfeeding Patients: Balancing Maternal Blood Pressure Control and Infant Safety

Hypertension is a leading cause of death and disability in the United States, affecting nearly half of all Americans, according to the NIH. Postpartum hypertension is a clinically important form of hypertension that can be preexisting or arise during or after pregnancy. While the...

The silent pandemic: the overlooked toll of stroke compared to COVID-19

The COVID-19 pandemic will be remembered as one of the defining health crises of the modern era. The World Health Organization reported approximately 7 million deaths attributed to COVID-19 globall...

Impact of Extent of Surgical Resection on Survival in Patients With High-risk Neuroblastoma

Objective: The impact of extent of resection of the primary tumor on outcomes in patients with high-risk neuroblastoma (HRNB) remains uncertain. We evaluated this issue in patients with HRNB treated on a prospective trial of multimodality therapy. Summary of Background Data: Pati...

National mortality trends due to OSA and respiratory failure in U.S adults from 1999–2023

Obstructive sleep apnea (OSA) and respiratory failure (RF) represent increasing clinical and public health challenges in the United States, yet national trends in mortality remain underexplored. This study evaluates trends in mortality associated with OSA and RF to highlight targ...

Intravascular Lithotripsy for Calcified Vascular Lesions: Mechanisms, Techniques, Clinical Applications, and Future Directions

Vascular calcification complicates endovascular intervention by reducing vessel compliance, impairing device delivery and expansion, and increasing the risk of suboptimal procedural outcomes. Intravascular lithotripsy (IVL) has emerged as a calcium-modification strategy that uses...

The Impact of v‐SYMPHONY's Virtual Boot Camp on Trainee Transition From Residency to Fellowship

BACKGROUND: Starting a pediatric subspecialty fellowship presents numerous challenges to trainees. Virtual Symposium of Pediatric Hematology/Oncology of New York (v-SYMPHONY), an educational collaborative organized by 18 pediatric hematology-oncology (PHO) programs, initiated an...

Management of Patent Ductus Arteriosus in the Adult Population

Patent ductus arteriosus (PDA) is defined as a persistent communication between the pulmonary artery and the aorta that normally closes before birth. While the ductus arteriosus is an essential vascular shunt for a developing fetus, its failure to close can become pathologic. Mos...

Left Atrial Strain Impairment in Embolic Stroke of Undetermined Source: A Systematic Review and Meta-Analysis

Embolic stroke of undetermined source (ESUS) accounts for approximately one-third of all ischemic strokes. Atrial cardiomyopathy, independent of paroxysmal atrial fibrillation, is an increasingly recognized embolic substrate. Left atrial (LA) strain assessed by speckle-tracking e...

Inpatient outcomes after acute ischemic stroke in patients with leukemia: A retrospective observational cohort study

Abstract: INTRODUCTION: Leukemia is associated with a greater risk of stroke due to increased hypercoagulability and introduction of treatment modalities that increase the risk of thrombosis. METHODS: Using the 2015–2022 National Inpatient Sample database, a retrospective observa...

Menopausal Hormone Therapy and Cardiovascular Risk: Current Evidence and Treatment Recommendations

In 2025, the US Food and Drug Administration (FDA) removed its prior class-wide boxed warnings for menopausal hormone therapy (MHT), paving the way for increased clinical use. Menopause accelerates cardiovascular risk independently of chronological aging, manifesting as a 7.5% in...

Timing and Incidence of Airway Interventions Following Occipitocervical Fusion: A Retrospective Study Using the Nationwide Inpatient Sample 2017 to 2022

Background: Occipitocervical fusions (OCFs) are associated with adverse airway events. The period of airway compromise remains poorly defined. The objective of this study was to identify differences between OCF and posterior cervical fusion not involving the occipitocervical join...

A Randomized Controlled Trial Evaluating Negative Pressure Therapy (NPT) to Reduce Wound Complications Following Major Lower Extremity Amputation

Objective: This study hypothesizes that negative pressure therapy (NPT) reduces wound-healing complications following major amputation. Background: Major lower extremity amputation carries a high incidence of incisional complications. NPT reduces these complications in other area...

Safety and Performance of the Colovac Anastomosis Protection Device. A Pooled Analysis of Prospective Studies Compared With Diverting Loop Ileostomy (SAFE-2025)

Objective: To compare the safety and effectiveness of the Colovac Anastomosis Protection Device with standard diverting ostomy (DO) following low anterior resection (LAR) for rectal cancer. Summary Background Data: DO is standard of care (SOC) following LAR for rectal cancer but...

The History of Neurosurgery at New York Medical College and Westchester Medical Center

The history of the Department of Neurosurgery at the New York Medical College (NYMC) began in New York City in the early 20th century. The purpose of this manuscript is to educate on the history of neurosurgery at NYMC and Westchester Medical Center (WMC) from its early beginning...

Cardiac Myosin-Binding Protein C in Cardiovascular Disease

Cardiac myosin-binding protein C (cMyBPC) is an important sarcomeric regulatory protein that plays a key role in myocardial contraction and relaxation. Through its interactions with thick and thin filament proteins, cMyBPC helps regulate cross-bridge cycling and contributes signi...

Osimertinib-Associated Cardiotoxicity in EGFR-Mutant Non–Small Cell Lung Cancer: Mechanisms, Phenotypes, and Surveillance

Osimertinib, a third-generation EGFR-TKI, is now the standard first-line treatment for EGFR-mutant non–small cell lung cancer and is increasingly given in the adjuvant setting for up to 3 years and in combination with chemotherapy. As exposure has lengthened and shifted toward cu...

Pacemakers in Pediatric Patients

Pacemaker insertion in children presents unique challenges because of their small size and developing anatomy. Since pacemaker insertion is relatively uncommon in pediatric patients, and as a result, specialized technologies for this population remain limited and under-researched...

Efficacy and Safety of Baxdrostat for Patients With Uncontrolled or Resistant Hypertension: A Systematic Review and Meta-Analysis

We evaluated the efficacy and safety of baxdrostat in adults with uncontrolled or resistant hypertension. We searched PubMed, Scopus, Web of Science, and Cochrane CENTRAL from inception to January 2026. We included randomized controlled trials that involved hypertension patients...

Spine Centers in Northeastern United States: Assessing Similarities and Disparities to Build more Homogeneity Across the Country

PROPOSE OF REVIEW: Spine centers are common, but no standardized regulations govern their designation. Existing certifications are issued by multiple independent organizations and are not necessarily equivalent, while many centers remain non-accredited. Consequently, centers may...

Migraine-Associated Tinnitus and Vestibular Symptoms: a Clinical Synthesis and Conceptual Framework

Abstract Purpose of Review Migraine is increasingly recognized as a multisensory neurologic disorder whose manifestations extend beyond headache to include tinnitus, aural fullness, dizziness, vertigo, and motion sensitivity. This review synthesizes current clinical and mechanist...