Weill Cornell Medical Center

Exploring transcriptomic and genomic latent variable correction approaches in differential expression analysis

Abstract Background Differential expression analysis is a central tool for studying the biological processes altered in human diseases via transcriptomic signatures. However, transcriptomic datasets are systematically confounded by latent variables from two distinct sources: unme...

Truth, Reconciliation, and Transformation: Another Step Forward

In the aftermath of the murder of George Floyd, the American Academy of Pediatrics (AAP) Board of Directors published a policy statement entitled "Truth, Reconciliation and Transformation: Continuing on the Path to Equity."1 The statement acknowledged historical transgressions an...

Axillary Nodal Upstaging in cT1N0 Invasive Lobular Carcinoma

OBJECTIVE: To determine whether sentinel lymph node biopsy (SLNB) omission is applicable to stage 1 invasive lobular breast cancer (ILC). BACKGROUND: The SOUND and INSEMA randomized controlled trials demonstrated that SLNB omission is noninferior to performing SLNB in early-stage...