Water Research Institute

Development of a Translational Assay for Identification and Quantitation of Orthologous Proteins to Aid Drug Development in Preclinical Models

Abstract Unequivocal identification and reproducible quantitation of proteins are key components of research and development activity in drug discovery. In some cases, the target protein might be a protein highly conserved across species; antibody-based assays are not specific en...

Inter- and intraspecific niche differences of four co-occurring Baetidae (Insecta: Ephemeroptera) in a mountain stream

Abstract Quantifying niche occupation and breadth among co-occurring aquatic species is a key challenge in ecology, especially in alpine streams where environmental variability can mask or reduce the effects of competition. This study investigated the niche position, breadth and...

Long-term temperature, oxygen and water clarity trends in Swiss lakes

Abstract. Water temperature, electrical conductivity, dissolved oxygen concentration, and water clarity are key variables routinely measured in Swiss lakes by lake monitoring programs run by cantonal environmental offices and international lake commissions. In most lakes, data is...

An interpretable remote sensing–machine learning framework for wildfire soil burn severity prediction in the northwestern United States

Background Although soil burn severity (SBS) is traditionally mapped post-fire, pre-fire predictive approaches remain limited despite their potential to identify areas at risk of soil degradation, runoff and erosion. Aim To develop a large-scale model for predicting post-fire SBS...

A high-resolution perspective on climate drivers of lake stratification and phototrophic community dynamics in Late Glacial Central Europe

Abstract. Predicting the trajectory of aquatic deoxygenation under global warming requires a mechanistic understanding of lacustrine responses to rapid climate shifts. We investigated how climate-driven changes in catchment vegetation and local iron-rich lithology regulated lake...