Washington DC VA Medical Center

Factors Associated with Persistently Increased IL-6 Levels in People with HIV

BACKGROUND: Individuals with HIV remain at higher risk of non-communicable diseases associated with interleukin-6-specific (IL-6) inflammation compared to the background population. Despite antiretroviral therapy, some individuals exhibit persistent hyperinflammation. We characte...

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

ABSTRACT Objective Susac syndrome (SS) is a rare CD8 + T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteom...