Wangjing Hospital of China Academy of Chinese Medical Sciences

Topographic analysis of choroidal thickness in pachychoroid disease using ultra-widefield swept-source optical coherence tomography

Purpose To characterise regional and topographic choroidal thickness (CT) profiles using ultra-widefield swept-source optical coherence tomography (UWF SS-OCT) and to compare topographic CT between normal eyes and eyes with pachychoroid disease. Methods All participants underwent...

A Hippo-YAP pathway activity-guided multimodal framework highlights NDRG1-associated tumor microenvironmental features in hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is characterized by marked molecular and histopathological heterogeneity, which limits the performance of conventional clinicopathological risk stratification systems. Hippo-YAP signaling is closely involved in HCC progression and tumor microenviron...