Virginia Cancer Specialists

From technology transfer to systems transformation: CGIAR's ways of working through a just transition lens

Just transition has emerged as an important framework for ensuring that agrifood systems transformation is not only environmentally sustainable but also socially equitable. This paper examines the extent to which the Consultative Group for International Agricultural Research (CGI...

Acquired resistance to the RAS(ON) multi-selective inhibitor daraxonrasib guides rational combination therapy strategies in pancreatic cancer

Abstract Daraxonrasib is an orally bioavailable RAS(ON) multi-selective tri-complex inhibitor of the oncogenic mutant and wild-type variants of N, H and KRAS. We previously reported encouraging efficacy in a phase 1/2 clinical trial evaluating daraxonrasib monotherapy at clinical...