Institution
Victor Babeș University of Medicine and Pharmacy Timișoara
Recent research
- AI & ComputingOpen access
Background: Azelaic acid, an established dermatologic dicarboxylic acid, was previously nominated as an unusual anticancer repurposing candidate. However, it remains unclear whether physicochemical properties, predicted ADME, or structural proximity to established endocrine antic...
- Health & MedicineOpen access
Lipoprotein(a) [Lp(a)] is a highly heritable apoB-containing lipoprotein and a causal contributor to atherosclerotic cardiovascular disease that may contribute to residual cardiovascular risk after myocardial infarction (MI), while the clinical benefit of selective pharmacologica...
- BiologyOpen access
Betaine Contribution to Performance Enhancement in Sport
Betaine is a compound with significant implications in exercise biology due to its ability to optimize metabolic homeostasis and exercise capacity. This narrative review analyzes the physiological and biochemical mechanisms by which betaine influences neuromuscular performance an...
- BiologyOpen access
Background/Objectives: Romania reports among the highest rates of carbapenem-resistant Gram-negative bacteria in the European Union, but patient-level data on healthcare-associated infections (HAIs) are scarce. We characterised carbapenem resistance, in-hospital outcomes, and car...
- Health & MedicineOpen access
Background: Pleural infection remains associated with substantial morbidity, mortality, and frequent treatment escalation. This systematic review and meta-analysis evaluated routinely available prognostic factors associated with adverse clinical outcomes in adults with pleural in...
- Health & MedicineOpen access
Background/Objectives: The apolipoprotein B/apolipoprotein A1 (ApoB/ApoA1) ratio has been proposed as an integrated marker of atherogenic and anti-atherogenic lipoprotein balance. This study assessed its association with the presence and angiographic severity of coronary artery d...
- Materials & EnergyOpen access
Background/Objectives: One of the major problems facing the medical world is cancer, which causes millions of deaths each year. Nitrogen-containing heterocycles appear to offer a potential solution to this problem. Thus, the present study aimed to synthesize and characterize—both...
- Health & MedicineOpen access
The fetal fraction (FF) of cell-free DNA determines the reliability of non-invasive prenatal testing (NIPT); whether first-trimester placental biomarkers add information beyond maternal factors is unclear. We linked NIPT samples from a single fetal medicine center over ten years...
- Health & MedicineOpen access
ABSTRACT Hundreds of herbal medicines are currently marketed for the management of acute respiratory infections (ARIs). However, there is uncertainty about their benefits and harms, and clinical guidance remains unclear. Our objective was to evaluate the benefits and harms of her...
- Health & MedicineOpen access
Background: Fosmanogepix is a first-in-class Gwt1 inhibitor with oral and intravenous formulations and broad in vitro activity, but its clinical evidence is scattered across small trials and case reports. We reviewed all identifiable human data from the searched sources on its ef...
- Health & MedicineOpen access
Olorofim, the first orotomide antifungal, is active against Aspergillus spp., Lomentospora prolificans, Scedosporium spp. and Coccidioides spp. We reviewed published clinical reports of olorofim in invasive fungal disease (IFD) with limited or no treatment options. PubMed/MEDLINE...
- Health & MedicineOpen access
Background and Objectives: Penile prosthesis infection usually ends in device removal, whereas unnecessarily broad or prolonged prophylaxis causes toxicity and promotes resistance. We assessed whether the systemic perioperative antibacterial or antifungal strategy, dose or durati...
- Health & MedicineOpen access
Background/Objectives: Neonatal diaphragm ultrasound measurements may vary with body size. We examined associations between birth weight and repeated bilateral diaphragm measurements during the first 48 h after birth. Methods: This exploratory secondary post hoc analysis included...
- Health & MedicineOpen access
Background/Objectives: Broad-range bacterial 16S rRNA gene PCR followed by sequencing may improve the etiological diagnosis of infective endocarditis (IE), particularly when conventional cultures are negative. This systematic review and meta-analysis evaluated the overall molecul...
- Health & MedicineOpen access
Chronic obstructive pulmonary disease (COPD) is a chronic progressive respiratory disease characterized by respiratory symptoms and airflow limitation and is one of the leading causes of morbidity and mortality worldwide. The evolution of the disease is associated with episodes o...
- Health & MedicineOpen access
Background and Objectives: The 11–13+6-week scan has evolved from a nuchal translucency (NT) measurement into an early anatomical survey, and the anomalies it identifies increasingly shape prenatal counselling and management. Data from Central and Eastern European screening popul...
- Health & MedicineOpen access
Purpose: This study aimed to describe the current management of patients with keratoconus in European and Middle Eastern countries through the collection of real-world data from clinicians actively managing keratoconus. Methods: Computer-assisted web interviewing survey targeting...
- Health & MedicineOpen access
Background/Objectives: Noninvasive imaging of the skin in the assessment of basal cell carcinoma (BCC) is a promising field of research. Ultrasound stands out because of its ease of use, low price point and versatility. Ex vivo ultrasound can be used to obtain detailed measuremen...
- Health & Medicine
BACKGROUND: Leiomyomas are the most common benign uterine tumors, whereas uterine sarcomas are rare malignant neoplasms associated with high morbidity and mortality. Differentiation using imaging remains challenging because of overlapping radiologic features. PURPOSE: To evaluate...
- Health & MedicineOpen access
The anterior condylar confluence of Trolard and its venous tributaries: an anatomical review
Abstract The anterior condylar confluence (ACC) of Trolard is a small extracranial venous plexus at the external orifice of the hypoglossal canal. Described over 150 years ago and present in the classical French anatomical literature, it was largely absent from the Anglophone rad...