Vi Technology (United States)

Designof Chiral Antimony Catalyst for Ring-OpeningReaction of Epoxides with Anilines

Abstract Pnictogen-bonding catalysis has emerged as a promising tool for noncovalent transformations; however, its application in asymmetric catalysis remains in its infancy, largely due to the scarcity of efficient chiral catalysts and activating modes. Herein, we report a new c...

HEPES: A Unique Case of Conformational Multi-ZwitterionicPolymorphism

Abstract HEPES (2-[4-(2-hydroxyethyl)piperazin-1-yl]ethane-1-sulfonic acid) is a widely used buffering agent in biological and biomedical research. Here, we reveal an exceptional solid-form landscape for HEPES. In addition to the two previously known polymorphs, we discover and c...